교수
이연 LEE, Yan
생체 재료화학 연구실
LAB Website
LAB Website
OFFICE
503-122
/
02-880-4344
LAB
503-101,130
/
02-880-4359
E-MAIL gacn@snu.ac.kr
연구내용
The objectives of our research group are to understand molecular-level interactions between biological systems and external signals, to control the interactions by synthetic molecules, and to develop new artificial materials on the basis of the interactions. Especially, our group wants to develop key molecular modules for efficient penetration into biosystems, for selective response to physical, chemical, or biological signals, and for escape from severe toxicity or foreign body reactions. We wants to combine the key molecular modules for overcoming the current limitations of biomaterials in clinical applications.
학력
- Ph. D. Chemistry, Seoul National University, Korea, 2005
- M. S. Chemistry, Seoul National University, Korea, 2001
- B. S. Chemistry, Seoul National University, Korea, 1999
주요 경력
- Professor, Department of Chemistry, Seoul National University, Korea, 2022-Present
- Associate Professor, Department of Chemistry, Seoul National University, Korea, 2014-2022
- Assistant Professor, Department of Chemistry, Seoul National University, Korea, 2009-2014
- Project Assistant Professor, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2008-2009.
- Postdoctoral Fellow, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2005-2008.
주요 논문
- JACS Au 2021, 1, 11, 2070-2079 “Dynamics and entropy of cyclohexane rings control pH-responsive reactivity”
- ACS Applied Materials & Interfaces 2020, 12, 30198-30212 “Covalently grafted 2-methacryloyloxyethyl phosphorylcholine networks inhibit fibrous capsule formation around silicone breast implants in a porcine model”
- Chemical Communications 2019, 55, 10222-10225 “Guanidine cyclic diimides and their polymers”
- Advanced Science 2018, 5, 1800240 “Multimeric amphipathic α-helical sequences for rapid and efficient intracellular protein transport at nanomolar concentrations”
- Angewandte Chemie International Edition 2014, 53, 10086-10089 “Cell penetrating, dimeric α-helical peptides are nanomolar inhibitors of HIV-1 transcription”
논문 검색
Yan Lee, Kazunori Kataoka
Ji-Hun Seo, Ryosuke Matsuno, Yan Lee, Madoka Takai, Kazuhiko Ishihara
Yan Lee, Takehiko Ishii, Horacio Cabral, Hyun Jin Kim, Ji-Hun Seo, Nobuhiro Nishiyama, Hiroki Oshima, Kensuke Osada, Kazunori Kataoka
Heebeom Koo, Geun-woo Jin, Hyunseo Kang, Yan Lee, Hye Yeong Nam, Hyung-suk Jang, Jong-Sang Park
Heebeom Koo, Hyunseo Kang, Yan Lee
Yan Lee, Kanjiro Miyata, Makoto Oba, Takehiko Ishii, Shigeto Fukushima, Muri Han, Hiroyuki Koyama, Nobuhiro Nishiyama, Kazunori Kataoka
Yan Lee, Min Yi Cho, Heejung Mo, Kihoon Nam, Heebeom Koo, Geun-woo Jin, Jong-Sang Park
Yan Lee, Shigeto Fukushima, Younsoo Bae, Shigehiro Hiki, Takehiko Ishii, Kazunori Kataoka
Tai Hwan Ha, Sun Ok Jung, Jeong Min Lee, Kun Yeong Lee, Yan Lee, Jong-Sang Park, Bong Hyun Chung
Yan Lee, Heejung Mo, Heebeom Koo, Jong-Yeun Park, Min Yi Cho, Geun-woo Jin, Jong-Sang Park