교수
이연 LEE, Yan
생체 재료화학 연구실
LAB Website
LAB Website
OFFICE
503-122
/
02-880-4344
LAB
503-101,130
/
02-880-4359
E-MAIL gacn@snu.ac.kr
연구내용
The objectives of our research group are to understand molecular-level interactions between biological systems and external signals, to control the interactions by synthetic molecules, and to develop new artificial materials on the basis of the interactions. Especially, our group wants to develop key molecular modules for efficient penetration into biosystems, for selective response to physical, chemical, or biological signals, and for escape from severe toxicity or foreign body reactions. We wants to combine the key molecular modules for overcoming the current limitations of biomaterials in clinical applications.
학력
- Ph. D. Chemistry, Seoul National University, Korea, 2005
- M. S. Chemistry, Seoul National University, Korea, 2001
- B. S. Chemistry, Seoul National University, Korea, 1999
주요 경력
- Professor, Department of Chemistry, Seoul National University, Korea, 2022-Present
- Associate Professor, Department of Chemistry, Seoul National University, Korea, 2014-2022
- Assistant Professor, Department of Chemistry, Seoul National University, Korea, 2009-2014
- Project Assistant Professor, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2008-2009.
- Postdoctoral Fellow, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2005-2008.
주요 논문
- JACS Au 2021, 1, 11, 2070-2079 “Dynamics and entropy of cyclohexane rings control pH-responsive reactivity”
- ACS Applied Materials & Interfaces 2020, 12, 30198-30212 “Covalently grafted 2-methacryloyloxyethyl phosphorylcholine networks inhibit fibrous capsule formation around silicone breast implants in a porcine model”
- Chemical Communications 2019, 55, 10222-10225 “Guanidine cyclic diimides and their polymers”
- Advanced Science 2018, 5, 1800240 “Multimeric amphipathic α-helical sequences for rapid and efficient intracellular protein transport at nanomolar concentrations”
- Angewandte Chemie International Edition 2014, 53, 10086-10089 “Cell penetrating, dimeric α-helical peptides are nanomolar inhibitors of HIV-1 transcription”
논문 검색
Dong Ryeol Lee, Ji Su Park, Il Hak Bae, Yan Lee, B. Moon Kim
Minwoo Noh, Sunah Kang, Yeongbong Mok, So Jung Choi, Jeongseon Park, Jannick Kingma, Ji-Hun Seo, Yan Lee
45. Unlocking the pH-Responsive Degradability of Fumaramic Acid Derivatives Using Photoisomerization
Wonmin Choi, Sunyoung Kang, Yeongbong Mok, Euddeum Park, Youngjun Song, So Jung Choi, Yan Lee
Soonsil Hyun, Seonju Lee, Seoyeon Kim, Sangmok Jang, Jaehoon Yu, Yan Lee
43. Alleviation of Capsular Formations on Silicone Implants in Rats using Biomembrane-mimicking Coatings
Ji Ung Park, Jiyeon Ham, Sukwha Kim, Ji-Hun Seo, Sang-Hyon Kim, Seonju Lee, Hye Jeong Min, Sunghyun Choi, Ra Mi Choi, Heejin Kim, Sohee Oh, Ji An Hur, Tae Hyun Choi, Yan Lee
Sangmok Jang, Soonsil Hyun, Seoyeon Kim, Seonju Lee, Im-Soon Lee, Masanori Baba, Yan Lee, Jaehoon Yu
Sunyoung Kang, Euddeum Park, Youngeun Kim, Seonju Lee, Jiwoong Kwon, Hyungdo Cho, Yan Lee
Sunyoung Kang, Youngeun Kim, Youngjun Song, Jin Uk Choi, Euddeum Park, Wonmin Choi, Jeongseon Park, Yan Lee
Daichi Nakayama, Yeongbong Mok, Minwoo Noh, Jeongseon Park, Sunyoung Kang, Yan Lee
Heejin Kim, Wonmin Choi, Seonju Lee, Sooyeol Kim, Jiyeon Ham, Ji-Hun Seo, Sangmok Jang, Yan Lee
