Faculty

DEPARTMENT OF CHEMISTRY, SEOUL NATIONAL UNIVERSITY.

Professor

Lee, Yan

Biomaterials Chemistry Lab.
LAB Website
OFFICE 503-122 / +82-2-880-4344
LAB 503-101,130 / +82-2-880-4359

Research Topic

The objectives of our research group are to understand molecular-level interactions between biological systems and external signals, to control the interactions by synthetic molecules, and to develop new artificial materials on the basis of the interactions. Especially, our group wants to develop key molecular modules for efficient penetration into biosystems, for selective response to physical, chemical, or biological signals, and for escape from severe toxicity or foreign body reactions. We wants to combine the key molecular modules for overcoming the current limitations of biomaterials in clinical applications.

Education

  • Ph. D. Chemistry, Seoul National University, Korea, 2005
  • M. S. Chemistry, Seoul National University, Korea, 2001
  • B. S. Chemistry, Seoul National University, Korea, 1999

Career

  • Professor, Department of Chemistry, Seoul National University, Korea, 2022-Present
  • Associate Professor, Department of Chemistry, Seoul National University, Korea, 2014-2022
  • Assistant Professor, Department of Chemistry, Seoul National University, Korea, 2009-2014
  • Project Assistant Professor, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2008-2009.
  • Postdoctoral Fellow, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2005-2008.

Papers

  1. JACS Au 2021, 1, 11, 2070-2079 “Dynamics and entropy of cyclohexane rings control pH-responsive reactivity”
  2. ACS Applied Materials & Interfaces 2020, 12, 30198-30212 “Covalently grafted 2-methacryloyloxyethyl phosphorylcholine networks inhibit fibrous capsule formation around silicone breast implants in a porcine model”
  3. Chemical Communications 2019, 55, 10222-10225 “Guanidine cyclic diimides and their polymers”
  4. Advanced Science 2018, 5, 1800240 “Multimeric amphipathic α-helical sequences for rapid and efficient intracellular protein transport at nanomolar concentrations”
  5. Angewandte Chemie International Edition 2014, 53, 10086-10089 “Cell penetrating, dimeric α-helical peptides are nanomolar inhibitors of HIV-1 transcription”

Search Papers

Dae Hee Cheon, Yoonhwa Choi, Rekha Arya, Yuna Hur, Hyeong Woon Choe, So Hee Nam, Soonsil Hyun, Akhilesh Kumar Chaurasia, Jaehoon Yu, Kyeong Kyu Kim, Yan Lee
Biomaterials, 2026, 328, (2026-05-01) Link
Minjae Kim, Jungwoo Kim, Minji Kang, So Hee Nam, Chi Heon Kim, Yan Lee, Sung Bae Park
Biomaterials Science, 2026, 14, 6, (2026-02-13) Link
Sunyoung Kang, Serena Serin Park, Sugyeong Jeong, Seoyeon Kyung, Minjae Kim, Seok Kyun Yun, Hyun-Na Kim, Seunghyun Kang, Yan Lee
Advanced Healthcare Materials, 2026, 15, 12, (2025-11-26) Link
David Koam, Ha Yeon Park, Dong Sun Kim, Hyeong Jin Kwon, Yan Lee, Kyobum Kim, Mitsuru Naito, Hyun Jin Kim
BIOMACROMOLECULES, 2025, 26(2), (98) Link
Anashwara Babu, Gomathi Sivakumar, Minjae Kim, Deepika Chauhan, Rahul Badri, Zlata Nagorna, Pradip Kar, Pijus K. Sasmal, Joachim F. R. Van Guyse, Susanta Banerjee, Yan Lee, Samarendra Maji
ACS Biomaterial Science & Engineering, 2025, 11, 11, (2025-11-10) Link
So Jung Choi, Hokyung Lee, Ho Min Park, Sunyoung Kang, Hyoyong Kim, Byeong-Woo Kang, Beom Soo Son, So Hyun Kim, Do Yup Lee, Yan Lee
Biomacromolecules, 2025, 26, 8, (2025-08-11) Link
Yunjung Choi, Joo-Yeong Jeon, Jeongin Hwang, Sejong Choi, Ki-Myo Kim, Ji-Ung Park, Yan Lee
Redox Biology, 2025, 81, (2025-04-01) Link
Yeonsoo Lim, Gyunam Park, Hojin An, Jonghwa Han, Joonhyun Bae, Ji-Hyun Kim, Yan Lee, Kyungtae Kang, Jaeyoung Sung, Sunbum Kwon
Angewandte Chemie International Edition, 2025, 64, 14, (2025-04-01) Link
Yujeong Jung, Soo Bin Ahn, Taeyang An, Hyeon-Min Cha, Minjae Kim, Hyunjin Cheon, Yejin Jang, Haemi Lee, Byungil Kim, Meehyein Kim, Yan Lee
ACS CENTRAL SCIENCE, 2024, 10, 8, (2024-08-28) Link
Dong Sun Kim, Younghun Kim, Dongwhan Lee, Yan Lee
Chemistry - A European Journal, 2024, 30, 15, (2024-03-12) Link