Faculty

DEPARTMENT OF CHEMISTRY, SEOUL NATIONAL UNIVERSITY.

Professor

LEE, Yan

Biomaterials Chemistry Lab.
LAB Website
OFFICE 503-122 / +82-2-880-4344
LAB 503-101,130 / +82-2-880-4359

Research Topic

The objectives of our research group are to understand molecular-level interactions between biological systems and external signals, to control the interactions by synthetic molecules, and to develop new artificial materials on the basis of the interactions. Especially, our group wants to develop key molecular modules for efficient penetration into biosystems, for selective response to physical, chemical, or biological signals, and for escape from severe toxicity or foreign body reactions. We wants to combine the key molecular modules for overcoming the current limitations of biomaterials in clinical applications.

Education

  • Ph. D. Chemistry, Seoul National University, Korea, 2005
  • M. S. Chemistry, Seoul National University, Korea, 2001
  • B. S. Chemistry, Seoul National University, Korea, 1999

Career

  • Professor, Department of Chemistry, Seoul National University, Korea, 2022-Present
  • Associate Professor, Department of Chemistry, Seoul National University, Korea, 2014-2022
  • Assistant Professor, Department of Chemistry, Seoul National University, Korea, 2009-2014
  • Project Assistant Professor, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2008-2009.
  • Postdoctoral Fellow, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2005-2008.

Papers

  1. JACS Au 2021, 1, 11, 2070-2079 “Dynamics and entropy of cyclohexane rings control pH-responsive reactivity”
  2. ACS Applied Materials & Interfaces 2020, 12, 30198-30212 “Covalently grafted 2-methacryloyloxyethyl phosphorylcholine networks inhibit fibrous capsule formation around silicone breast implants in a porcine model”
  3. Chemical Communications 2019, 55, 10222-10225 “Guanidine cyclic diimides and their polymers”
  4. Advanced Science 2018, 5, 1800240 “Multimeric amphipathic α-helical sequences for rapid and efficient intracellular protein transport at nanomolar concentrations”
  5. Angewandte Chemie International Edition 2014, 53, 10086-10089 “Cell penetrating, dimeric α-helical peptides are nanomolar inhibitors of HIV-1 transcription”

Search Papers

Taeyang An, Byeongwoo Kang, Sunyoung Kang, Jinyoung Pac, Jihea Youk, Dian Lin, Yan Lee
Chemical Communications, 2019, 55, 69, (2019-09-07) Link
Sunyoung Kang, Gee Ho Park, Seulah Kim, Jungah Kim, Yoonhwa Choi, Yan Huang, Yan Lee, Tae Hyun Choi
Advanced Healthcare Materials, 2019, 8, 14, (2019-07-01) Link
Minji Kang, Sungwhan Kim, Heejin Kim, Youngjun Song, Dongwook Jung, Sunah Kang, Ji-Hun Seo, Sohee Nam, Yan Lee
ACS Applied Materials & Interfaces, 2019, 11, 8, (2019-02-27) Link
Heejin Kim, Sungwhan Kim, Sunyoung Kang, Youngjun Song, Suyong Shin, Seonju Lee, Minji Kang, So Hee Nam, Yan Lee
Angewandte Chemie-International Edition, 2018, 57, 38, (2018-09-17) Link
Eun Joung Choi, Dongwook Jung, Jong-Seo Kim, Yan Lee, B. Moon Kim
Chemistry-A European Journal, 2018, 24, 43, (2018-08-01) Link
Jae Hoon Oh, Seung-Eun Chong, Sohee Nam, Soonsil Hyun, Sejong Choi, Hyojun Gye, Sangmok Jang, Joomyung Jang, Sung Won Hwang, Jaehoon Yu, Yan Lee
Advanced Science, 2018, 5, 8, (2018-08-01) Link
Soonsil Hyun, Yuno Lee, Sun Mi Jin, Jane Cho, Jeemin Park, Changbong Hyeon, Key-Sun Kim, Yan Lee, Jaehoon Yu
ACS Central Science, 2018, 4, 7, (2018-07-25) Link
Gyu Chan Kim, Joon Hyung Ahn, Jae Hoon Oh, Sohee Nam, Soonsil Hyun, Jaehoon Yu, Yan Lee
Biomacromolecules, 2018, 19, 7, (2018-07-09) Link
Soonsil Hyun, Yoonhwa Choi, Ha Neul Lee, Changki Lee, Donghoon Oh, Dong-Ki Lee, Changjin Lee, Yan Lee, Jaehoon Yu
Chemical Science, 2018, 9, 15, (2018-04-21) Link
Seung-Ryong Kwon, So Hee Nam, Clara Yongjoo Park, Seol Baek, Joomyung Jang, Xiangguo Che, Su Hong Kwak, Yu-Ra Choi, Na-Rae Park, Je-Yong Cho, Yan Lee, Taek Dong Chung
Advanced Functional Materials, 2018, 28, 15, (2018-04-11) Link