Faculty

DEPARTMENT OF CHEMISTRY, SEOUL NATIONAL UNIVERSITY.

Professor

LEE, Yan

Biomaterials Chemistry Lab.
LAB Website
OFFICE 503-122 / +82-2-880-4344
LAB 503-101,130 / +82-2-880-4359

Research Topic

The objectives of our research group are to understand molecular-level interactions between biological systems and external signals, to control the interactions by synthetic molecules, and to develop new artificial materials on the basis of the interactions. Especially, our group wants to develop key molecular modules for efficient penetration into biosystems, for selective response to physical, chemical, or biological signals, and for escape from severe toxicity or foreign body reactions. We wants to combine the key molecular modules for overcoming the current limitations of biomaterials in clinical applications.

Education

  • Ph. D. Chemistry, Seoul National University, Korea, 2005
  • M. S. Chemistry, Seoul National University, Korea, 2001
  • B. S. Chemistry, Seoul National University, Korea, 1999

Career

  • Professor, Department of Chemistry, Seoul National University, Korea, 2022-Present
  • Associate Professor, Department of Chemistry, Seoul National University, Korea, 2014-2022
  • Assistant Professor, Department of Chemistry, Seoul National University, Korea, 2009-2014
  • Project Assistant Professor, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2008-2009.
  • Postdoctoral Fellow, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2005-2008.

Papers

  1. JACS Au 2021, 1, 11, 2070-2079 “Dynamics and entropy of cyclohexane rings control pH-responsive reactivity”
  2. ACS Applied Materials & Interfaces 2020, 12, 30198-30212 “Covalently grafted 2-methacryloyloxyethyl phosphorylcholine networks inhibit fibrous capsule formation around silicone breast implants in a porcine model”
  3. Chemical Communications 2019, 55, 10222-10225 “Guanidine cyclic diimides and their polymers”
  4. Advanced Science 2018, 5, 1800240 “Multimeric amphipathic α-helical sequences for rapid and efficient intracellular protein transport at nanomolar concentrations”
  5. Angewandte Chemie International Edition 2014, 53, 10086-10089 “Cell penetrating, dimeric α-helical peptides are nanomolar inhibitors of HIV-1 transcription”

Search Papers

Yan Lee, Kazunori Kataoka
Advances in Polymer Science, 2012, 249, (2012-01-01) Link
Ji-Hun Seo, Ryosuke Matsuno, Yan Lee, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Acta Biomaterialia, 2011, 7, 4, (2011-04-01) Link
Frederico Pittella, Mingzhen Zhang, Yan Lee, Hyun J. Kim, Theofilus Tockary, Kensuke Osada, Takehiko Ishii, Kanjiro Miyata, Nobuhiro Nishiyama, Kazunori Kataoka
Biomaterials, 2011, 32, 11, (2011-04-01) Link
Heejin Kim, Seonju Lee, Minwoo Noh, So Hyun Lee, Yeongbong Mok, Geun-woo Jin, Ji-Hun Seo, Yan Lee
Polymer, 2011, 52, 6, (2011-03-10) Link
Geun-woo Jin, Heebeom Koo, Kihoon Nam, Heejin Kim, Seonju Lee, Jong-Sang Park, Yan Lee
Polymer, 2011, 52, 2, (2011-01-21) Link
Hyun Jin Kim, Atsushi Ishii, Kanjiro Miyata, Yan Lee, Shourong Wu, Makoto Oba, Nobuhiro Nishiyama, Kazunori Kataoka
Journal of Controlled Release, 2010, 145, 2, (2010-07-14) Link
Mai Sanjoh, Shigehiro Hiki, Yan Lee, Makoto Oba, Kanjiro Miyata, Takehiko Ishii, Kazunori Kataoka
Macromolecular Rapid Communications, 2010, 31, 13, (2010-07-01) Link
Kanjiro Miyata, Noha Gouda, Hiroyasu Takemoto, Makoto Oba, Yan Lee, Hiroyuki Koyama, Yuichi Yamasaki, Keiji Itaka, Nobuhiro Nishiyama, Kazunori Kataoka
Biomaterials, 2010, 31, 17, (2010-06-01) Link
Yan Lee, Takehiko Ishii, Hyun Jin Kim, Nobuhiro Nishiyama, Yoshiyuki Hayakawa, Keiji Itaka, Kazunori Kataoka
Angewandte Chemie-International Edition, 2010, 49, 14, (2010-03-29) Link
Heebeom Koo, Geun-woo Jin, Hyunseo Kang, Yan Lee, Kihoon Nam, Cheng Zhe Bai, Jong-Sang Park
Biomaterials, 2010, 31, 5, (2010-02-01) Link