교수

김병문 Kim, Byeong Moon

합성 및 의약화학 연구실
LAB Website

OFFICE 503동 625호 / 02-880-6644

LAB 503-607,608,628 / 02-880-6644

RESEARCH AREAS

# 유기화학

연구내용

Our research in organic chemistry is focused on the development of efficient synthetic methodologies related to the synthesis of physiologically important compounds and the advancement of chiral catalysts aimed at practical asymmetric synthesis. Towards this goal, various heterogeneous media for catalyst immobilization are being actively pursued. Another major research interest of our group involves medicinal chemistry programs including the design and synthesis of various receptor ligands and enzyme inhibitors in connection with therapeutic intervention of human diseases such as obesity, depression and cancer. These medicinal chemistry approaches utilizes essential tools such as peptidomimetics and smart library construction.

학력

Ph.D. Chemistry, Messachusetts Institute of Technology, USA, 1988
M.S. Chemistry, Seoul National University, Korea, 1982
B.S. Chemistry, Seoul National University, Korea, 1980

주요 경력

Research Fellow, MIT, USA, 1988-1990

주요 논문

“Structure-Activity Relationships of Fluorene Compounds Inhibiting HCV Variants” Kim, H. S.; You, Y.; Mun, J. G.; Gadhed, C. G.; Moon, H.; Lee, J. S.; Pae, A. N.; Kohara, M.; Keum, G.; Kim, B. M.; Chang, S. K. Antiviral Research, 2020, 174, 104678.
“AuPd–Fe3O4 nanoparticle-catalyzed synthesis of furan-2,5-dimethylcarboxylate from biomass-derived 5-hydroxymethylfurfural under mild conditions.” Cho, A.; Byun, S.; Cho, J. H.; Kim, B. M. ChemSusChem, 2019, 12, 2310-2317.
"Synthesis of arenesulfonyl fluorides via sulfuryl fluoride incorporation from arynes" Kwon, J.; Kim, B. M. Org. Lett. 2019, 21, 428–433.
“Chemoselective Tyrosine Bioconjugation through Sulfate Click Reaction.” Choi, E. J.; Jung, D.; Kim, S.-S.; Lee, Y.; Kim, B. M., Chem-Eur. J. 2018, 24, 10948-10952.
“AuPd−Fe3O4 Nanoparticle Catalysts for Highly Selective, One‐Pot Cascade Nitro‐Reduction and Reductive Amination” Cho, A.; Byun, S.; Kim, B. M. Adv. Synth. Catal. 2018, 360, 1253-1261.
“Heterogenized bimetallic Pd–Pt–Fe3O4 nanoflakes as extremely robust, magnetically recyclable catalysts for selective nitroarene reduction” Byun, S.; Song, Y.; Kim, B. M. ACS Appl. Mater. Interfaces, 2016, 8, 14637-14647.