Surface enhanced Raman scattering (SERS) is a mature technique to detect the molecules with high selectivity and sensitivity. However, how to make the SERS signals repeatable and quantitative, and how to have deeper understanding on the chemical enhancement mechanism are still big challenges. Recently, graphene, as well as the other two dimensional materials, was developed to use as a Raman enhancement substrate, which was demonstrated to be promising to overcome the issues in conventional SERS substrate. In this talk, the multi-role of graphene played in SERS is overviewed in turn, including a Raman probe, a substrate, an additive and a building block of a flat surface for SERS. Apart from versatile improvements on the SERS performance towards applications, graphene-involved SERS studies are also expected to shed light on the fundamental mechanism of SERS effect.