Development of Copper-Catalyzed Asymmetric Synthetic Methods of Organoboron Compounds
Date : November 22, 2018 16:30 ~
Speaker : Prof. Jae Sook Yoon
Location : Mogam Hall, Bldg 500
Organoboron compounds are versatile intermediates in synthetic organic chemistry.
Transition-metal catalyzed additions of boron reagents to carbon–carbon multiple bonds have
become important tools for the synthesis of organoboron derivatives. My research group has
previously developed catalytic asymmetric reactions using copper catalysts with high levels of
regio- and enantioselectivity; asymmetric conjugate reduction, asymmetric borylation and
hydroboration.1
In this seminar, I will present our recent developments in the field of copper-catalyzed
stereoselective synthesis of organoboron compounds,2 including tandem C–C bond forming
reactions using boron-containing organocopper species (I and II) and asymmetric
hydroboration of 1,1-disubstituted alkenes.