Our research focuses on the oxidative coupling to develop a novel and efficient bond-formation method between two nucleophiles. We have successfully developed three generations of oxidative coupling. In addition, in-depth understanding toward the reactions is the other focus. Recently, a new series of oxidative coupling reactions have been developed. New insights into the reaction mechanism have also been revealed by operando X-ray absorption, Raman, electron paramagnetic resonance, and nuclear magnetic resonance spectroscopy.