Seminars

DEPARTMENT OF CHEMISTRY, SEOUL NATIONAL UNIVERSITY.

Novel synthetic entries towards carbocyclic and heterocyclic beta-amino acid derivatives

June 13, 2012l Hit 201
Date : June 19, 2012 17:00 ~
Speaker : Prof. Dr. ir. Norbert De Kimpe
Location : Rm.L-307, Bldg.500
Date : 2012. 6. 19, 5:00 PM Place : Rm.L-307, Bldg.500 -Abstract- Several new entries towards the title beta-amino acid derivatives will be unraveled. Heavily functionalized aziridine and azetidine derivatives, carrying the beta-amino acid motif will be discussed. Focus will be given to numerous new compounds in chiral and achiral form. Some peculiar rearrangements of heterocycles will be highlighted. A novel highly enantioselective funtionalized ester and amide synthesis will be presented. These entries provide a very large selection of new compounds suitable for screening purposes in agrochemistry and pharmaceutical sciences. In addition, the link towards foldamer formation will be given using peptide chemistry.