Date: 2009. 6. 16, 4:00 PM Place: Rm. 404, Bldg 503 -Abstract- Catecholamines are typical neurotransimitters that are used in neural signal transmission process. These molecules are selectively recognized by a specific receptor as "key and lock" relation. It is a one of typical biological molecular recognition processes however detail of recognition mechanism has not been revealed in molecular level. Thus molecular structures and dynamics without solvent perturbations are indispensable informations to understand the mechanism. We have been studying UV and IR spectra of catecholamine related molecules such as tyramine [1], dopa and synephrine in a supersonic jet. The catecholamines are evapolated graphite matrix laser desorption source [2]. In S1-S0 electronic spectrum of DOPA molecule, sharp vibronic bands in the S1 excited state are observed clearly for the first time. UV-UV Hole burning spectroscopy [1, 3] are also was measured and found that dopa has onlyt a single stable conformation in a jet condition in spite of the flexible chain. The IR spectrum measure by the IR dip spectroscopy [4] shows well-resolved vibrational transitions in the ground state. From the comparison to theoretical vibrational spectra, the detail of the molecular geometry are analysied. The relation between the chromopher and the conformer will be discussed. [References] [1] K. Makara et al., J.Phys.Chem.A112,13463s(2008). [2] L. Li and D. M. Lubman, Rev.Sci.Inst.,59,557(1988);G.Meijeretal.,App.Phys.B-51,395(1990);I.Hunig,Chem.Phys.Lett.,369,173(2003);F.Piuzzietal.,Chem.Phys.Lett.,320,282(2000);H.Saigusaetal.,Chem.Phys.Lett.,418,119(2006) [3] T. Ebata, Chapter 6, NonlinearSpectroscopyforMolecularStructureDetermination,Eds.R.W.Field,etal..;BlackwellScience,Cambridge,1998.;S.Ishiuchi,etal.J.Phys.Chem.A111,7569(2007). [4]S.Tanabeetal.,ChemPhys.Lett.,215,347(1993);Y.Koizumietal.,J.Chem.Phys.,129, 104311 (2008)