Professor
LEE, Yan
Biomaterials Chemistry Lab.
LAB Website
LAB Website
OFFICE
503-122
/
+82-2-880-4344
LAB
503-101,130
/
+82-2-880-4359
E-MAIL gacn@snu.ac.kr
Research Topic
The objectives of our research group are to understand molecular-level interactions between biological systems and external signals, to control the interactions by synthetic molecules, and to develop new artificial materials on the basis of the interactions. Especially, our group wants to develop key molecular modules for efficient penetration into biosystems, for selective response to physical, chemical, or biological signals, and for escape from severe toxicity or foreign body reactions. We wants to combine the key molecular modules for overcoming the current limitations of biomaterials in clinical applications.
Education
- Ph. D. Chemistry, Seoul National University, Korea, 2005
- M. S. Chemistry, Seoul National University, Korea, 2001
- B. S. Chemistry, Seoul National University, Korea, 1999
Career
- Professor, Department of Chemistry, Seoul National University, Korea, 2022-Present
- Associate Professor, Department of Chemistry, Seoul National University, Korea, 2014-2022
- Assistant Professor, Department of Chemistry, Seoul National University, Korea, 2009-2014
- Project Assistant Professor, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2008-2009.
- Postdoctoral Fellow, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2005-2008.
Papers
- JACS Au 2021, 1, 11, 2070-2079 “Dynamics and entropy of cyclohexane rings control pH-responsive reactivity”
- ACS Applied Materials & Interfaces 2020, 12, 30198-30212 “Covalently grafted 2-methacryloyloxyethyl phosphorylcholine networks inhibit fibrous capsule formation around silicone breast implants in a porcine model”
- Chemical Communications 2019, 55, 10222-10225 “Guanidine cyclic diimides and their polymers”
- Advanced Science 2018, 5, 1800240 “Multimeric amphipathic α-helical sequences for rapid and efficient intracellular protein transport at nanomolar concentrations”
- Angewandte Chemie International Edition 2014, 53, 10086-10089 “Cell penetrating, dimeric α-helical peptides are nanomolar inhibitors of HIV-1 transcription”
Search Papers
Yeongbong Mok, Daichi Nakayama, Minwoo Noh, Sangmok Jang, Taeho Kim, Yan Lee
Minwoo Noh, Yeongbong Mok, Daichi Nakayama, Sangmok Jang, Seonju Lee, Taeho Kim, Yan Lee
Jong Woo Lee, Seonju Lee, Sangmok Jang, Kyu Young Han, Younggyu Kim, Jaekyung Hyun, Seong Keun Kim, Yan Lee
Sang Yoon Lee, Yan Lee, Joon Sig Choi, Jong-Sang Park, Myung-Un Choi, Sang Yoon Lee
Songhie An, Kihoon Nam, Sunghyun Choi, Cheng Z Bai, Yan Lee, Jong-Sang Park
Geun-woo Jin, Heejin Kim, Ji-Hun Seo, Jiyeon Ham, Jong-Sang Park, Yan Lee
Sangmok Jang, Seonju Lee, Heejin Kim, Jiyeon Ham, Ji-Hun Seo, Yeongbong Mok, Minwoo Noh, Yan Lee
Minwoo Noh, Yeongbong Mok, Seonju Lee, Heejin Kim, So Hyun Lee, Geun-woo Jin, Ji-Hun Seo, Heebeom Koo, Tae Ha Park, Yan Lee
Hyung-Suk Jang, Yan Lee, Tae-Il Kim, Jong-Sang Park, Joon Sig Choi
Min J. Kwon, Songhie An, Sunghyun Choi, Kihoon Nam, Hye S. Jung, Chang S. Yoon, Jung H. Ko, Hye J. Jun, Tae K. Kim, Soo J. Jung, Jeong H. Park, Yan Lee, Jong-Sang Park