Professor
LEE, Yan
Biomaterials Chemistry Lab.
LAB Website
LAB Website
OFFICE
503-122
/
+82-2-880-4344
LAB
503-101,130
/
+82-2-880-4359
E-MAIL gacn@snu.ac.kr
Research Topic
The objectives of our research group are to understand molecular-level interactions between biological systems and external signals, to control the interactions by synthetic molecules, and to develop new artificial materials on the basis of the interactions. Especially, our group wants to develop key molecular modules for efficient penetration into biosystems, for selective response to physical, chemical, or biological signals, and for escape from severe toxicity or foreign body reactions. We wants to combine the key molecular modules for overcoming the current limitations of biomaterials in clinical applications.
Education
- Ph. D. Chemistry, Seoul National University, Korea, 2005
- M. S. Chemistry, Seoul National University, Korea, 2001
- B. S. Chemistry, Seoul National University, Korea, 1999
Career
- Professor, Department of Chemistry, Seoul National University, Korea, 2022-Present
- Associate Professor, Department of Chemistry, Seoul National University, Korea, 2014-2022
- Assistant Professor, Department of Chemistry, Seoul National University, Korea, 2009-2014
- Project Assistant Professor, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2008-2009.
- Postdoctoral Fellow, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2005-2008.
Papers
- JACS Au 2021, 1, 11, 2070-2079 “Dynamics and entropy of cyclohexane rings control pH-responsive reactivity”
- ACS Applied Materials & Interfaces 2020, 12, 30198-30212 “Covalently grafted 2-methacryloyloxyethyl phosphorylcholine networks inhibit fibrous capsule formation around silicone breast implants in a porcine model”
- Chemical Communications 2019, 55, 10222-10225 “Guanidine cyclic diimides and their polymers”
- Advanced Science 2018, 5, 1800240 “Multimeric amphipathic α-helical sequences for rapid and efficient intracellular protein transport at nanomolar concentrations”
- Angewandte Chemie International Edition 2014, 53, 10086-10089 “Cell penetrating, dimeric α-helical peptides are nanomolar inhibitors of HIV-1 transcription”
Search Papers
Jeongseon Park, Heeyoung Joo, Minwoo Noh, Yon Namkoong, Seonju Lee, Kyung Hwa Jung, Hye Ryun Ahn, Seulah Kim, Jong-Chan Lee, Jae Hoon Yoon, Yan Lee
Myoungjin Lee, Heejin Kim, Jiae Seo, Minji Kang, Sunah Kang, Joomyung Jang, Yan Lee, Ji-Hun Seo
Young Ju Jin, Sunah Kang, Pona Park, Dongkil Choi, Dae Woo Kim, Dongwook Jung, Jaemoon Koh, Joohee Jeon, Myoungjin Lee, Jiyeon Ham, Ji-Hun Seo, Hong-Ryul Jin, Yan Lee
Youngjun Song, Dongwook Jung, Sunyoung Kang, Yan Lee
Yeongbong Mok, Minwoo Noh, Gyu Chan Kim, Youngjun Song, Heejin Kim, Seulah Kim, Sihyeong Yi, Ji-Hun Seo, Yan Lee
Seoyeon Kim, Soonsil Hyun, Yuri Lee, Yan Lee, Jaehoon Yu
Su Jeong Song, Seulgi Lee, Yan Lee, Joon Sig Choi
Sunah Kang, Myoungjin Lee, Minji Kang, Minwoo Noh, JooHee Jeon, Yan Lee, Ji-Hun Seo
Byeongho Lee, Kunzhou Li, Hong Sik Yoon, Jeyong Yoon, Yeongbong Mok, Yan Lee, Hong H. Lee, Yong Hyup Kim
Jeongseon Park, Minwoo Noh, Min Keun Chey, Yeongbong Mok, Ji-Hun Seo, Yan Lee