Associate Professor
Song, Woon Ju
Bioinorganic chemistry laboratory
LAB Website
LAB Website
OFFICE
503-224
/
+82-2-880-4374
LAB
503-203,232
/
+82-2-880-6636
E-MAIL woonjusong@snu.ac.kr
Research Topic
Our research lies in the interdisciplinary studies of inorganic chemistry, biochemistry, protein engineering that we employ spectroscopic, kinetic, thermodynamic, and biochemical techniques/analysis to understand orchestrated chemical reactions of metalloproteins and metalloenzymes. We aim to design and synthesize metal/protein-based biocatalysts and biomaterials that can be further adapted for targeting structures and/or functionalities. Additionally, we are interested in the creation of bioinorganic tools to regulate biological systems such as antibiotic resistance, bacterial communications, and carbon and nitrogen fixation pathways.
Education
- Ph.D. Inorganic Chemistry, MIT, USA, 2011 (Prof. Stephen J. Lippard)
- M.S. Chemistry, Ewha Womans University, Republic of Korea, 2005 (Prof. Wonwoo Nam)
- B.S. Science/Chemistry Education, Ewha Womans University, Republic of Korea, 2003
Career
- Assistant Professor, Department of Chemistry, Seoul National University, Republic of Korea, 2016-Present
- Postdoctoral Scholar, Department of Chemistry and Biochemistry, University of California, San Diego, USA, 2011-2015 (Prof. F. Akif Tezcan)
Papers
- "Proteins as Diverse, Efficient, and Evolvable Scaffolds for Artificial Metalloenzymes" Chem. Commun., 2020. 56, 9586-9599
- “Discovery of Novel Gene Functions by Chemistry-Guided Targeted Sequence Analysis” Biochemistry, 2020, 59, 10-11
- "Diverse protein assembly driven by metal and chelating amino acids with selectivity and tunability" Nat. Commun., 2019, 10, 5545
- "Emergence of Metal Selectivity and Promiscuity in Metalloenzymes" J. Biol. Inorg. Chem., 2019, 24, 517-531
- “Integrative Metagenomic and Biochemical Studies on Rifamycin ADP-ribosyltransferases Discovered in the Sediment Microbiome" Sci. Rep. 2018, 8, 12143
- “Importance of Scaffold Flexibility/Rigidity in the Design and Directed Evolution of Artificial Metallo-β-lactamases" J. Am. Chem. Soc. 2017, 139, 16772
Search Papers
Inseo Choi, Jaehee Lee, Kyohyun Hwang, Sebastian Kunze, Jae Wan Park, Seung Jun Hwang, Jongwoo Lim, Seunghoon Lee, Woon Ju Song
Junyoung Park, Juhee Hahm, Junhyeong Yim, Hyelim Lee, Hwan Min Hwang, Soyeon Lee, Ju-Young Park, Arun Velladurai, Jagadeesh Kumar Gangasani, Hana Cho, Hankum Park, Minju Lee, Jeehee Lee, Hyunuk Eom, Woon Ju Song, Sanghee Lee, Eunha Kim, Jongmin Park
Jaewon Lee, Woon Ju Song
Woo Jae Jeong, Seoungjun Ha, Woon Ju Song
Yunjong Lee, Jaewon Moon, Kyu Jin Son, Jaehee Lee, Seoungjun Ha, Woon Ju Song
Hye Won Kim, Sangwook Kang, Sihyeon Kim, Hyunbin Lee, Yegang Hur, Woon Ju Song, Dong-Chan Oh, Seokhee Kim
Minjung Han, Sun-heui Yoon, Jaehee Lee, Taek Dong Chung, Woon Ju Song
23. Discovery of highly active kynureninases for cancer immunotherapy through protein language model
Hyunuk Eom, Sukhwan Park, Kye Soo Cho, Jihyeon Lee, Hyunbin Kim, Stephanie Kim, Jinsol Yang, Young-Hyun Han, Juyong Lee, Chaok Seok, Myeong Sup Lee, Woon Ju Song, Martin Steinegger
Jaehee Lee, Jaewon Moon, Inseo Choi, Yunjong Lee, Woon Ju Song
Tobias Vornholt, Florian Leiss-Maier, Woo Jae Jeong, Cathleen Zeymer, Woon Ju Song, Gerard Roelfes, Thomas R. Ward


