Our goal is to develop a new generation of biosensors, therapeutic agents, or cell-based assays created from highly functional nanomaterials/structures and biomolecules important in human disease and health. Major application areas of developed constructs/methods include in vitro bioassay and in vivo imaging-based disease diagnostics, interfacing biologically functional surface with cells of interest, drug delivery, and synthetic cell biology.

• Ph.D. Chemistry, Northwestern University, Evanston, IL, USA, 2004
• B.S. and M.S. Chemistry, Hanyang University, Seoul, South Korea

• Consultant, Nanosphere, Inc., Northbrook, IL, USA, 2004
• Postdoctoral Research Fellow, Department of Chemistry, University of California, Berkeley and Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA (Advisor: Prof. Jay T. Groves): 2004-2005
• Associate Professor, School of Chemistry, Seoul National University: 2006-Current
• Scientific Advisory Board Member, Medifron DBT: 2006-Current

1. Nanogap-Engineerable, Raman-Active Nanodumbbells for Single-Molecule Detection, Nature Materials, 9, 50 (2010).
2. Highly Uniform and Reproducible Surface-Enhanced Raman Scattering from DNA-Tailorable Nanoparticles with 1-nm Interior Gap, Nature Nanotechnology, 6, 452 (2011).
3. Plasmonic Nanogap-Enhanced Raman Scattering with Nanoparticles, Accounts of Chemical Research, 49, 2746 (2016).
4. Nano-Bio Computing Lipid Nanotablet, Science Advances, 5, eaau2124 (2019).
5. One-Pot Heterointerfacial Metamorphosis for Synthesis and Control of Widely Varying Heterostructured Nanoparticles, Journal of the American Chemical Society, 143, 3383 (2021).
6. Mechanically Interlocked Gold Nanocatenanes, Nature Synthesis, 1, 649 (2022)