Associate Professor
Song, Woon Ju
Bioinorganic chemistry laboratory
LAB Website
LAB Website
OFFICE
503-224
/
+82-2-880-4374
LAB
503-203,232
/
+82-2-880-6636
E-MAIL woonjusong@snu.ac.kr
Research Topic
Our research lies in the interdisciplinary studies of inorganic chemistry, biochemistry, protein engineering that we employ spectroscopic, kinetic, thermodynamic, and biochemical techniques/analysis to understand orchestrated chemical reactions of metalloproteins and metalloenzymes. We aim to design and synthesize metal/protein-based biocatalysts and biomaterials that can be further adapted for targeting structures and/or functionalities. Additionally, we are interested in the creation of bioinorganic tools to regulate biological systems such as antibiotic resistance, bacterial communications, and carbon and nitrogen fixation pathways.
Education
- Ph.D. Inorganic Chemistry, MIT, USA, 2011 (Prof. Stephen J. Lippard)
- M.S. Chemistry, Ewha Womans University, Republic of Korea, 2005 (Prof. Wonwoo Nam)
- B.S. Science/Chemistry Education, Ewha Womans University, Republic of Korea, 2003
Career
- Assistant Professor, Department of Chemistry, Seoul National University, Republic of Korea, 2016-Present
- Postdoctoral Scholar, Department of Chemistry and Biochemistry, University of California, San Diego, USA, 2011-2015 (Prof. F. Akif Tezcan)
Papers
- "Proteins as Diverse, Efficient, and Evolvable Scaffolds for Artificial Metalloenzymes" Chem. Commun., 2020. 56, 9586-9599
- “Discovery of Novel Gene Functions by Chemistry-Guided Targeted Sequence Analysis” Biochemistry, 2020, 59, 10-11
- "Diverse protein assembly driven by metal and chelating amino acids with selectivity and tunability" Nat. Commun., 2019, 10, 5545
- "Emergence of Metal Selectivity and Promiscuity in Metalloenzymes" J. Biol. Inorg. Chem., 2019, 24, 517-531
- “Integrative Metagenomic and Biochemical Studies on Rifamycin ADP-ribosyltransferases Discovered in the Sediment Microbiome" Sci. Rep. 2018, 8, 12143
- “Importance of Scaffold Flexibility/Rigidity in the Design and Directed Evolution of Artificial Metallo-β-lactamases" J. Am. Chem. Soc. 2017, 139, 16772
Search Papers
Tobias Vornholt, Florian Leiss-Maier, Woo Jae Jeong, Cathleen Zeymer, Woon Ju Song, Gerard Roelfes, Thomas R. Ward
Soyeun Son, Woon Ju Song
Woo Jae Jeong, Jaehee Lee, Hyunuk Eom, Woon Ju Song
18. Underlying Role of Hydrophobic Environments in Tuning Metal Elements for Efficient Enzyme Catalysis
Hyunuk Eom, Yuanxin Cao, Hyunsoo Kim, Sam P. de Visser, Woon Ju Song
Jaehee Lee, Woon Ju Song
Jaehee Lee, Minwoo Yang, Woon Ju Song
Hwanjin Joo, Hyunuk Eom, Youna Cho, Mina Rho, Woon Ju Song
Woo Jae Jeong, Woon Ju Song
Se-Min Jung, Minwoo Yang, Woon Ju Song