Associate Professor
Song, Woon Ju
Bioinorganic chemistry laboratory
LAB Website
LAB Website
OFFICE
503-224
/
+82-2-880-4374
LAB
503-203,232
/
+82-2-880-6636
E-MAIL woonjusong@snu.ac.kr
Research Topic
Our research lies in the interdisciplinary studies of inorganic chemistry, biochemistry, protein engineering that we employ spectroscopic, kinetic, thermodynamic, and biochemical techniques/analysis to understand orchestrated chemical reactions of metalloproteins and metalloenzymes. We aim to design and synthesize metal/protein-based biocatalysts and biomaterials that can be further adapted for targeting structures and/or functionalities. Additionally, we are interested in the creation of bioinorganic tools to regulate biological systems such as antibiotic resistance, bacterial communications, and carbon and nitrogen fixation pathways.
Education
- Ph.D. Inorganic Chemistry, MIT, USA, 2011 (Prof. Stephen J. Lippard)
- M.S. Chemistry, Ewha Womans University, Republic of Korea, 2005 (Prof. Wonwoo Nam)
- B.S. Science/Chemistry Education, Ewha Womans University, Republic of Korea, 2003
Career
- Assistant Professor, Department of Chemistry, Seoul National University, Republic of Korea, 2016-Present
- Postdoctoral Scholar, Department of Chemistry and Biochemistry, University of California, San Diego, USA, 2011-2015 (Prof. F. Akif Tezcan)
Papers
- "Proteins as Diverse, Efficient, and Evolvable Scaffolds for Artificial Metalloenzymes" Chem. Commun., 2020. 56, 9586-9599
- “Discovery of Novel Gene Functions by Chemistry-Guided Targeted Sequence Analysis” Biochemistry, 2020, 59, 10-11
- "Diverse protein assembly driven by metal and chelating amino acids with selectivity and tunability" Nat. Commun., 2019, 10, 5545
- "Emergence of Metal Selectivity and Promiscuity in Metalloenzymes" J. Biol. Inorg. Chem., 2019, 24, 517-531
- “Integrative Metagenomic and Biochemical Studies on Rifamycin ADP-ribosyltransferases Discovered in the Sediment Microbiome" Sci. Rep. 2018, 8, 12143
- “Importance of Scaffold Flexibility/Rigidity in the Design and Directed Evolution of Artificial Metallo-β-lactamases" J. Am. Chem. Soc. 2017, 139, 16772
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