Exploring New Synthetic Strategies in Asymmetric Synthesis
소속 :
연사 : Ming-Hua Xu(Chinese Academy of Sciences)
일시 : 2012-03-26 17:00 ~
장소 : 500동 목암홀
일 시 : 2012년 3월 26일, 5:00 PM
장 소 : 500동 목암홀
-Abstract-
New discoveries for efficient asymmetric synthesis of various optically pure compounds continues to be a pivotal subject in modern organic chemistry. In this lecture, our recent efforts in developing new methodologies, new strategies, as well as new chiral catalysts for stereoselective C-C bond formation will be introduced. Asymmetric syntheses of various structurally important molecules such as chiral homoallylic amines, diarylmethylamines, isoindolinones and α-hydroxy ketones/esters with excellent diastereoselectivities and/or enantioselectivities have been achieved particularly by using chiral sulfur chemistry, chiral olefin catalysis, and chiral sulfur-olefin strategy. In addition, the synthetic value of some of the approaches developed has been demonstrated in several pharmacologically interesting molecules syntheses.
장 소 : 500동 목암홀
-Abstract-
New discoveries for efficient asymmetric synthesis of various optically pure compounds continues to be a pivotal subject in modern organic chemistry. In this lecture, our recent efforts in developing new methodologies, new strategies, as well as new chiral catalysts for stereoselective C-C bond formation will be introduced. Asymmetric syntheses of various structurally important molecules such as chiral homoallylic amines, diarylmethylamines, isoindolinones and α-hydroxy ketones/esters with excellent diastereoselectivities and/or enantioselectivities have been achieved particularly by using chiral sulfur chemistry, chiral olefin catalysis, and chiral sulfur-olefin strategy. In addition, the synthetic value of some of the approaches developed has been demonstrated in several pharmacologically interesting molecules syntheses.
