Developing Therapeutic Antibodies and Proteins by Rational Design and Knowledge-based Combinatorial Methods
소속 :
연사 : 선정훈 박사님(Eli Lilly and Company AME, La Jolla, CA)
일시 : 2012-01-16 11:00 ~
장소 : 503동 104호(세미나실)
일 시 : 2012년 1월 16일, 11:00 AM
장 소 : 503동 104호(세미나실)
-Abstract-
Multiple examples in recombinant protein and antibody engineering will be presented. These examples demonstrate how to devise strategies and perform custom experiments to solve problems facing molecules in various developmental stages. The problems include aggregation, heterogeneity issues, low solubility, low stability, troubled secretion, mis-folding and compromised function. The target molecules are antibodies, antibody fragments, soluble receptors, ligands, and fusion proteins.
장 소 : 503동 104호(세미나실)
-Abstract-
Multiple examples in recombinant protein and antibody engineering will be presented. These examples demonstrate how to devise strategies and perform custom experiments to solve problems facing molecules in various developmental stages. The problems include aggregation, heterogeneity issues, low solubility, low stability, troubled secretion, mis-folding and compromised function. The target molecules are antibodies, antibody fragments, soluble receptors, ligands, and fusion proteins.
