일 시 : 2011년 11월 17일, 오후 5:00
장 소 : 500동 목암홀

-Abstract-
   Bioprobes are reporter molecules which can be used to monitor biological events in vivo and ex vivo. Fluorescent molecules have become prominent materials for the development of bioprobes in various fields of application due to their high sensitivity and visual/real-time detection capability. The conventional bioprobe design has been carried out by so-called hypothesis-driven approach. Therefore, the scope of bioprobe development is intrinsically limited by the available knowledge for the target. An alternative approach is diversity-driven approach, in which abroad range of fluorescence molecules in a library format are constructed by combinatorial chemistry, as a tool-box for unbiased screening. Herein recent results on the fluorescents library that could serve as valuable for diversity-driven bioprobe development of Stem Cell, Muscle Sensors, and Muscle differentiation, will be discussed.