화학부교수

DEPARTMENT OF CHEMISTRY, SEOUL NATIONAL UNIVERSITY.

  1. Home
  2. 교수/연구
  3. 교수소개
  4. 화학부교수

화학부교수

교수

김병문 Kim, Byeong Moon

합성 및 의약화학 연구실
LAB Website
OFFICE 503동 625호 / 02-880-6644
LAB 503-607,608,628 / 02-880-6644
RESEARCH AREAS
# 유기화학

김병문 교수

김병문 교수 사진

연구내용

Our research in organic chemistry is focused on the development of efficient synthetic methodologies related to the synthesis of physiologically important compounds and the advancement of chiral catalysts aimed at practical asymmetric synthesis. Towards this goal, various heterogeneous media for catalyst immobilization are being actively pursued. Another major research interest of our group involves medicinal chemistry programs including the design and synthesis of various receptor ligands and enzyme inhibitors in connection with therapeutic intervention of human diseases such as obesity, depression and cancer. These medicinal chemistry approaches utilizes essential tools such as peptidomimetics and smart library construction.

학력

  • Ph.D. Chemistry, Messachusetts Institute of Technology, USA, 1988
  • M.S. Chemistry, Seoul National University, Korea, 1982
  • B.S. Chemistry, Seoul National University, Korea, 1980

주요 경력

  • Research Fellow, MIT, USA, 1988-1990

주요 논문

  1. “Structure-Activity Relationships of Fluorene Compounds Inhibiting HCV Variants” Kim, H. S.; You, Y.; Mun, J. G.; Gadhed, C. G.; Moon, H.; Lee, J. S.; Pae, A. N.; Kohara, M.; Keum, G.; Kim, B. M.; Chang, S. K. Antiviral Research, 2020, 174, 104678.
  2. “AuPd–Fe3O4 nanoparticle-catalyzed synthesis of furan-2,5-dimethylcarboxylate from biomass-derived 5-hydroxymethylfurfural under mild conditions.” Cho, A.; Byun, S.; Cho, J. H.; Kim, B. M. ChemSusChem, 2019, 12, 2310-2317.
  3. "Synthesis of arenesulfonyl fluorides via sulfuryl fluoride incorporation from arynes" Kwon, J.; Kim, B. M. Org. Lett. 2019, 21, 428–433.
  4. “Chemoselective Tyrosine Bioconjugation through Sulfate Click Reaction.” Choi, E. J.; Jung, D.; Kim, S.-S.; Lee, Y.; Kim, B. M., Chem-Eur. J. 2018, 24, 10948-10952.
  5. “AuPd−Fe3O4 Nanoparticle Catalysts for Highly Selective, One‐Pot Cascade Nitro‐Reduction and Reductive Amination” Cho, A.; Byun, S.; Kim, B. M. Adv. Synth. Catal. 2018, 360, 1253-1261.
  6. “Heterogenized bimetallic Pd–Pt–Fe3O4 nanoflakes as extremely robust, magnetically recyclable catalysts for selective nitroarene reduction” Byun, S.; Song, Y.; Kim, B. M. ACS Appl. Mater. Interfaces, 2016, 8, 14637-14647.

논문 검색

51. Peptide Deformylase Inhibitors with Retro-amide Scaffold: Synthesis and Structure-activity Relationships
Seung Kyu Lee, Kwang Hyun Choi, Sang Jae Lee, Se Won Suh, B. Moon Kim, Bong Jin Lee
Bioorganic & Medicinal Chemistry Letters, 2010, 20, 15, 4317-4319, (2010-08-01) Link
50. Use of an Ionic Liquid as a Co-solvent for Recyclable Pd/C-mediated N-Debenzylation
Jin Kyu Choi, Byung Sun Jeon, Jong Hyun Cho, B. Moon Kim
Bulletin of The Korean Chemical Society, 2010, 31, 3, 735-738, (2010-03-20) Link
49. Heterogeneous Asymmetric Henry Reaction using a Chiral bis(oxazoline)-copper Complex Immobilized on Magnetically Separable Mesocellular Mesoporous Silica Support
Jun-Mun Lee, Jaeyun Kim, Yongje Shin, Chang-Eun Yeom, Ji Eun Lee, Taeghwan Hyeon, B. Moon Kim
Tetrahedron-Asymmetry, 2010, 21, 3, 285-291, (2010-03-01) Link
48. Xylocydine, a Novel Cdk Inhibitor, is an Effective Inducer of Apoptosis in Hepatocellular Carcinoma Cells in vitro and in vivo
Seung-Ju Cho, Seung-Soo Lee, Young-Jong Kim, Byoung-Duck Park, Joon-Seok Choi, LinHua Liu, Young-Mi Ham, B. Moon Kim, Seung-Ki Lee
Cancer Letters, 2010, 287, 2, 196-206, (2010-01-28) Link
47. Acid-mediated Activation of Modified Ring-closing Metathesis Catalysts
Seyoung Kim, Wonmi Hwang, In Seon Lim, Sung Hye Kim, Sang-gi Lee, B. Moon Kim
Tetrahedron Letters, 2010, 51, 4, 709-713, (2010-01-27) Link
46. [76Br]BMK-I-152, a Non-peptide Analogue for PET Imaging of Corticotropin-releasing Hormone Type 1 Receptor (CRHR1)
L. Lang, Y. Ma, B. Moon Kim, E. M. Jagoda, K. C. Rice, L. P. Szajek, C. Contoreggi, P. W. Gold, G. P. Chrousos, W. C. Eckelman, D. O. Kiesewetter, L. Lang
Journal of Labelled Compounds and Radiopharmaceuticals, 2009, 52, 9, 394-400, (2009-07-01) Link
45. Preparation of Chiral Diamines by the Diaza-Cope Rearrangement (DCR)
Hyunwoo Kim, Soon Mog So, Jik Chin, B. Moon Kim
Aldrichimica Acta, 2008, 41, 3, 77-88, (2008-10-01) Link
44. Stereospecific Synthesis of C2 Symmetric Diamines from the Mother Diamine by Resonance-Assisted Hydrogen-Bond Directed Diaza-Cope Rearrangement
Hyunwoo Kim, Yen Nguyen, Cindy Pai-Hui Yen, Leonid Chagal, Alan J. Lough, B. Moon Kim, Jik Chin
Journal of The American Chemical Society, 2008, 130, 36, 12184-12191, (2008-09-10) Link
43. Synthesis and Structural Analysis of 6-Aminobicyclo[2.2.1]heptane-2-carboxylic Acid as a Conformationally Constrained γ-Turn Mimic
Jin-Seong Park, Kyoung Rak Kim, Hye Young Nam, Chang-Eun Yeom, Chieyeon Chough, Soon Ho Kwon, Seonggu Ro, Dong-Kyu Shin, B. Moon Kim
Protein and Peptide Letters, 2008, 15, 9, 980-984, (2008-09-01) Link
42. A Short Synthesis of Conformationally Constrained Unnatural Bicyclic Amino Acids Containing a Nitrogen Atom at the Ring Juncture: (9aR)- and (9aS)-Octahydropyrido[1,2-a]pyrazine-(3S)-carboxylic Acids (Opc)
Soon Mog So, Chang-Eun Yeom, Seong Mi Cho, Soo Young Choi, Young Keun Chung, B. Moon Kim
Synlett, 2008, 2008, 5, 702-706, (2008-03-01) Link
로그인 ENGLISH