교수

김병문 Kim, Byeong Moon

합성 및 의약화학 연구실
LAB Website

OFFICE 503동 625호 / 02-880-6644

LAB 503-607,608,628 / 02-880-6644

RESEARCH AREAS

# 유기화학

연구내용

Our research in organic chemistry is focused on the development of efficient synthetic methodologies related to the synthesis of physiologically important compounds and the advancement of chiral catalysts aimed at practical asymmetric synthesis. Towards this goal, various heterogeneous media for catalyst immobilization are being actively pursued. Another major research interest of our group involves medicinal chemistry programs including the design and synthesis of various receptor ligands and enzyme inhibitors in connection with therapeutic intervention of human diseases such as obesity, depression and cancer. These medicinal chemistry approaches utilizes essential tools such as peptidomimetics and smart library construction.

학력

Ph.D. Chemistry, Messachusetts Institute of Technology, USA, 1988
M.S. Chemistry, Seoul National University, Korea, 1982
B.S. Chemistry, Seoul National University, Korea, 1980

주요 경력

Research Fellow, MIT, USA, 1988-1990

주요 논문

“Structure-Activity Relationships of Fluorene Compounds Inhibiting HCV Variants” Kim, H. S.; You, Y.; Mun, J. G.; Gadhed, C. G.; Moon, H.; Lee, J. S.; Pae, A. N.; Kohara, M.; Keum, G.; Kim, B. M.; Chang, S. K. Antiviral Research, 2020, 174, 104678.
“AuPd–Fe3O4 nanoparticle-catalyzed synthesis of furan-2,5-dimethylcarboxylate from biomass-derived 5-hydroxymethylfurfural under mild conditions.” Cho, A.; Byun, S.; Cho, J. H.; Kim, B. M. ChemSusChem, 2019, 12, 2310-2317.
"Synthesis of arenesulfonyl fluorides via sulfuryl fluoride incorporation from arynes" Kwon, J.; Kim, B. M. Org. Lett. 2019, 21, 428–433.
“Chemoselective Tyrosine Bioconjugation through Sulfate Click Reaction.” Choi, E. J.; Jung, D.; Kim, S.-S.; Lee, Y.; Kim, B. M., Chem-Eur. J. 2018, 24, 10948-10952.
“AuPd−Fe3O4 Nanoparticle Catalysts for Highly Selective, One‐Pot Cascade Nitro‐Reduction and Reductive Amination” Cho, A.; Byun, S.; Kim, B. M. Adv. Synth. Catal. 2018, 360, 1253-1261.
“Heterogenized bimetallic Pd–Pt–Fe3O4 nanoflakes as extremely robust, magnetically recyclable catalysts for selective nitroarene reduction” Byun, S.; Song, Y.; Kim, B. M. ACS Appl. Mater. Interfaces, 2016, 8, 14637-14647.

논문 검색

21. Autoradiographic Visualization of Corticotropin Releasing Hormone Type 1 Receptors with a Nonpeptide Ligand: Synthesis of [76Br]MJL-1-109-2

Elaine Jagoda, Carlo Contoreggi, Mei-Jing Lee, Chih-Hao K. Kao, Lawrence P. Szajek, Sam Listwak, Philip Gold, George Chrousos, Elisabeth Greiner, B. Moon Kim, Arthur E. Jacobson, Kenner C. Rice, William Eckelman

Journal of Medicinal Chemistry, 2003, 46, 17, 3559-3562, (2003-08-14) Link

20. A Novel Mesoporous Silica-Supported Lewis Acid Catalyst for CC Bond Formation Reactions in Water

Sang-Wook Kim, Taegwhan Hyeon, B. Moon Kim

Advanced Synthesis & Catalysis, 2003, 345, 8, 936-938, (2003-08-01) Link

19. Accommodation of α-Substituted Residues in the β-Peptide 12-Helix: Expanding the Range of Substitution Patterns Available to a Foldamer Scaffold

Jin-Seong Park, Hee-Seung Lee, Jonathan R. Lai, B. Moon Kim, Samuel H. Gellman

Journal of The American Chemical Society, 2003, 125, 28, 8539-8545, (2003-07-16) Link

18. Efficient Synthesis of Highly Functionalized Triquinane Derivatives through Dicobalt Octacarbonyl-Catalyzed Cycloaddition of Diyne with Diene under Carbon Monoxide Followed by Cleavage of a Double Bond

Seung Uk Son, Kang Hyun Park, Seung Jung Lee, B. Moon Kim, Young Keun Chung

Synlett, 2003, 2003, 8, 1101-1104, (2003-07-01) Link

17. Efficient Synthesis of Enantiomerically Pure β2-Amino Acids via Chiral Isoxazolidinones

Hee-Seung Lee, Jin-Seong Park, B. Moon Kim, Samuel H. Gellman