화학부교수

DEPARTMENT OF CHEMISTRY, SEOUL NATIONAL UNIVERSITY.

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화학부교수

교수

김병문 Kim, Byeong Moon

합성 및 의약화학 연구실
LAB Website
OFFICE 503동 625호 / 02-880-6644
LAB 503-607,608,628 / 02-880-6644
RESEARCH AREAS
# 유기화학

김병문 교수

김병문 교수 사진

연구내용

Our research in organic chemistry is focused on the development of efficient synthetic methodologies related to the synthesis of physiologically important compounds and the advancement of chiral catalysts aimed at practical asymmetric synthesis. Towards this goal, various heterogeneous media for catalyst immobilization are being actively pursued. Another major research interest of our group involves medicinal chemistry programs including the design and synthesis of various receptor ligands and enzyme inhibitors in connection with therapeutic intervention of human diseases such as obesity, depression and cancer. These medicinal chemistry approaches utilizes essential tools such as peptidomimetics and smart library construction.

학력

  • Ph.D. Chemistry, Messachusetts Institute of Technology, USA, 1988
  • M.S. Chemistry, Seoul National University, Korea, 1982
  • B.S. Chemistry, Seoul National University, Korea, 1980

주요 경력

  • Research Fellow, MIT, USA, 1988-1990

주요 논문

  1. “Structure-Activity Relationships of Fluorene Compounds Inhibiting HCV Variants” Kim, H. S.; You, Y.; Mun, J. G.; Gadhed, C. G.; Moon, H.; Lee, J. S.; Pae, A. N.; Kohara, M.; Keum, G.; Kim, B. M.; Chang, S. K. Antiviral Research, 2020, 174, 104678.
  2. “AuPd–Fe3O4 nanoparticle-catalyzed synthesis of furan-2,5-dimethylcarboxylate from biomass-derived 5-hydroxymethylfurfural under mild conditions.” Cho, A.; Byun, S.; Cho, J. H.; Kim, B. M. ChemSusChem, 2019, 12, 2310-2317.
  3. "Synthesis of arenesulfonyl fluorides via sulfuryl fluoride incorporation from arynes" Kwon, J.; Kim, B. M. Org. Lett. 2019, 21, 428–433.
  4. “Chemoselective Tyrosine Bioconjugation through Sulfate Click Reaction.” Choi, E. J.; Jung, D.; Kim, S.-S.; Lee, Y.; Kim, B. M., Chem-Eur. J. 2018, 24, 10948-10952.
  5. “AuPd−Fe3O4 Nanoparticle Catalysts for Highly Selective, One‐Pot Cascade Nitro‐Reduction and Reductive Amination” Cho, A.; Byun, S.; Kim, B. M. Adv. Synth. Catal. 2018, 360, 1253-1261.
  6. “Heterogenized bimetallic Pd–Pt–Fe3O4 nanoflakes as extremely robust, magnetically recyclable catalysts for selective nitroarene reduction” Byun, S.; Song, Y.; Kim, B. M. ACS Appl. Mater. Interfaces, 2016, 8, 14637-14647.

논문 검색

61. Short Synthesis of Enantiopure trans-3-Arylpiperazine-2-carboxylic Acid Derivatives via Diaza-Cope Rearrangement
Soon Ho Kwon, Sang Min Lee, Sang Moon Byun, Jik Chin, B. Moon Kim
Organic Letters, 2012, 14, 14, 3664-3667, (2012-07-20) Link
60. Enhanced Reactivity and Enantioselectivity in Catalytic Glyoxylate-ene Reactions Using Chiral Bis(oxazoline)–copper Complex in an Ionic Liquid
Mina Kim, Han Saem Jeong, Chang-Eun Yeom, B. Moon Kim
Tetrahedron-Asymmetry, 2012, 23, 13, 1019-1022, (2012-07-15) Link
59. [76Br]BMK-152, a Nonpeptide Analogue, with High Affinity and Low Nonspecific Binding for the Corticotropin-releasing Factor Type 1 Receptor
Elaine M. Jagoda, Lixin Lang, Karen Mccullough, Carlo Contoreggi, B. Moon Kim, Ying Ma, Kenner C. Rice, Lawrence P. Szajek, William C. Eckelman, Dale O. Kiesewetter, Elaine M. Jagoda
Synapse, 2011, 65, 9, 910-918, (2011-09-01) Link
58. Efficient and Chemoselective Reduction of Olefins Catalyzed by Fe3O4 Nanoparticles using Hydrazine Hydrate
Eunsuk Kim, Seyoung Kim, B. Moon Kim
Bulletin of The Korean Chemical Society, 2011, 32, 8, 3183-3186, (2011-08-20) Link
57. Fe3O4 Nanoparticles: A Conveniently Reusable Catalyst for the Reduction of Nitroarenes Using Hydrazine Hydrate
Seyoung Kim, Eunsuk Kim, B. Moon Kim
Chemistry-An Asian Journal, 2011, 6, 8, 1921-1925, (2011-08-01) Link
56. Ibulocydine Is a Novel Prodrug Cdk Inhibitor That Effectively Induces Apoptosis in Hepatocellular Carcinoma Cells
Seung-Ju Cho, Young-Jong Kim, Young-Joon Surh, B. Moon Kim, Seung-Ki Lee
Journal of Biological Chemistry, 2011, 286, 22, 19662-19671, (2011-06-03) Link
55. Simple One-pot Synthesis of Rh-Fe3O4 Heterodimer Nanocrystals and Their Applications to a Magnetically Recyclable Catalyst for Efficient and Selective Reduction of Nitroarenes and Alkenes
Youngjin Jang, Seyoung Kim, Samuel Woojoo Jun, Byung Hyo Kim, Sunhwan Hwang, In Kyu Song, B. Moon Kim, Taeghwan Hyeon
Chemical Communications, 2011, 47, 12, 3601-3603, (2011-03-28) Link
54. Recycling of Osmium Catalyst in Oxidative Olefin Cleavage: A Chemoentrapment Approach
Seyoung Kim, Jooyoung Chung, B. Moon Kim
Tetrahedron Letters, 2011, 52, 12, 1363-1367, (2011-03-23) Link
53. Simple Synthesis of Pd-Fe3O4 Heterodimer Nanocrystals and Their Application as a Magnetically Recyclable Catalyst for Suzuki Cross-coupling Reactions
Youngjin Jang, Jooyoung Chung, Seyoung Kim, Samuel Woojoo Jun, Byung Hyo Kim, Dong Won Lee, B. Moon Kim, Taeghwan Hyeon
Physical Chemistry Chemical Physics, 2011, 13, 7, 2512-2516, (2011-02-21) Link
52. Peptide Deformylase Inhibitors with Non-peptide Scaffold: Synthesis and Structure–activity Relationships
Seung Kyu Lee, Kwang Hyun Choi, Sang Jae Lee, Jong Sun Lee, Ji Yun Park, B. Moon Kim, Bong Jin Lee
Bioorganic & Medicinal Chemistry Letters, 2011, 21, 1, 133-136, (2011-01-01) Link
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