14408
이연Associate Professor
  • E-MAILgacn@snu.ac.kr
  • ADDRESS503-101, 503-130

  • OFFICE+82-2-880-4344FAX+82-2-871-2496LAB+82-2-880-4359

Current Research Interests
The objective of our research group is the development of biosignal-responsive functional materials. Biosignals such as pH, temperature, reduction potentials, ionic strength can be used as the trigger for the effective control of the functional material activity. Based on the specificity and efficiency, the biosignal-responsive functional materials can be applied into the various fields, ranged from the bioimaging of the cells in the fundamental cell biology to the treatment of diseases in the clinical frontiers.

Education
B. S. Chemistry, Seoul National University, Korea, 1999

M. S. Chemistry, Seoul National University, Korea, 2001

Ph. D. Chemistry, Seoul National University, Korea, 2005

Research Experiences
Assistant Professor, Department of Chemistry, Seoul National University, Korea, 2009-Present.

Project Assistant Professor, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2008-2009.

Postdoctoral Fellow, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, the University of Tokyo, Japan, 2005-2008.

Recent Representative Publications
“Ring opening metathesis polymerization of bicyclic α,β-unsaturated anhydrides for ready-to-be-grafted polymers having tailored pH-responsive degradability”, Heejin Kim, Sungwhan Kim, Sunyoung Kang, Youngjun Song, Suyong Shin, Seonju Lee, Minji Kang, So Hee Nam and Yan Lee*, Angewandte Chemie International Edition 2018, 57, 12468-12472

“Multimeric amphipathic a-helical sequences for rapid and efficient intracellular protein transport at nanomolar concentrations”, Jae Hoon Oh, Sohee Nam, Seungeun Chong, Soonsil Hyun, Hyojun Gye, Sangmok Jang, Joonyung Jang, Sung Won Hwang, Jaehoon Yu,* and Yan Lee*, Advanced Science 2018, 1800240

“Systematic structure control of ammonium iodide salts as feasible UCST-type forward osmosis draw solutes for the treatment of highly concentrated wastewater”, Jeongseon Park, Heeyoung Joo, Minwoo Noh, Yon Namkoong, Seonju Lee, Kyung Hwa Jung, Hye Ryun Ahn, Seulah Kim, Jong-Chan Lee, Jae Hoon Yoon, and Yan Lee*, Journal of Materials Chemistry A 2018, 6, 1255-1265

“Anti-inflammatory and anti-bacterial effect of covalently attached biomembrane-mimic polymer grafts on Gore-Tex implants”, Young Ju Jin, Sunah Kang, Pona Park, Dongkil Choi, Dae Woo Kim, Dongwook Jung, Jaemoon Koh, Joohee Jeon, Myoungjin Lee, Ji-Hun Seo, Hong-Ryul Jin* and Yan Lee*, ACS Applied Materials & Interfaces 2017, 9 (22), 19161-19175

“Cell penetrating, dimeric a-helical peptides are nanomolar inhibitors of HIV-1 transcription”, Sangmok Jang, Soonsil Hyun, Seoyeon Kim, Seonju Lee, Im-Soon Lee, Masanori Baba, Yan Lee*, and Jaehoon Yu*, Angewandte Chemie International Edition 2014, 53, 10086-10089 (Hot papers)

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